Before GHS regulatory changes introduced the need for color printing on labels, continuous fanfolded labels were standard packaging for thermal transfer printers. While that may have fallen out of fashion, operators can still use our continuous Poly-Twin LX and EP fanfolded labels (which meet GHS standards) on both color inkjet and color laser/LED platforms.
The main advantage of continuous fanfolded labels is the number of labels that can be printed before operator involvement. With sheeted labels, you are limited by the size of the printer tray; with labels on rolls, you are limited by the maximum outside diameter a printer will accept (meaning you often get half as many labels as with a fanfolded stack). With fanfolded labels, you can print a full stack at one time.
There are both color inkjet and laser print platforms that are designed for continuous fanfolded labels, which are often the best operational choice for high volume hand-applied labeling. Brandywine can help you pick the right one for your product.